Acute Kidney Injury: Turning Early Action Into Better Care
- Dr. Natalia Orihuela — Nephrologist and Director of the Peritoneal Dialysis Program at DPU SRL, Montevideo, Uruguay, she also leads administrative and program management for adult and pediatric kidney transplant services
Nephrology
Acute kidney injury (AKI) is associated with increased morbidity, prolonged hospitalization, and risk of progression to chronic kidney disease, making early recognition and intervention essential. Timely assessment of serum creatinine, urine output, volume status, medication exposure, and potential underlying causes helps identify patients at risk. Management focuses on correcting reversible factors, optimizing fluid and hemodynamic status, treating infections, relieving urinary obstruction, and avoiding or adjusting potentially nephrotoxic medications. Serial monitoring of renal function, electrolytes, and fluid balance supports timely treatment adjustments. High-risk patients may require nephrology consultation and renal replacement therapy when clinically indicated. A proactive, multidisciplinary approach can prevent further kidney damage, reduce complications, and improve patient outcomes.