CRRT Prescription Parameters in Critically Ill Patients

• Dr. Abdulghani Kabli — Critical Care Consultant and Deputy Director of the Adult Critical Care Medicine Residency Training Program at King Faisal Specialist Hospital and Research Center, Jeddah, he specializes in Adult Critical Care and Critical Care Nephrology, with a strong focus on medical education and research

Nephrology · Critical Care

CRRT prescription requires selection of the appropriate modality, blood-flow rate, dialysate flow, replacement-fluid rate, treatment duration, net fluid removal, and anticoagulation strategy. The choice of modality depends on factors such as availability, the patient’s clinical condition, and the reason for CRRT. The source describes a typical blood-flow rate of 150–250 mL/min and a CRRT dose of 25–30 mL/kg/hour, divided between dialysate and replacement fluid according to the patient’s requirements. Net fluid removal should be individualized based on hemodynamic stability and the desired fluid balance. Treatment duration is commonly around 72 hours, reflecting the stated filter lifespan and concerns about declining efficacy.